B-[3-(2-naphthalenyl)phenyl]Boronic acid - Names and Identifiers
B-[3-(2-naphthalenyl)phenyl]Boronic acid - Physico-chemical Properties
Molecular Formula | C16H13BO2
|
Molar Mass | 248.08 |
Density | 1.23±0.1 g/cm3(Predicted) |
Boling Point | 486.0±48.0 °C(Predicted) |
pKa | 8.27±0.19(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
B-[3-(2-naphthalenyl)phenyl]Boronic acid - Introduction
3-(2-Naphthyl)phenylboronic acid is an organic compound with the chemical formula C16H13BO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- 3-(2-Naphthyl)phenylboronic acid is a white to pale yellow crystalline solid.
-It is insoluble in water at room temperature, but soluble in organic solvents such as ethanol, dimethylformamide, etc.
-The compound has good thermal and chemical stability.
Use:
- 3-(2-Naphthyl)phenylboronic acid is often used as an important reagent and intermediate in organic synthesis.
-It can be used to prepare other compounds, such as cross-coupling reactions involving phenylboronic acid, organometallic catalyzed reactions, etc.
-The compound is also used in the pharmaceutical field as an intermediate for the synthesis of active pharmaceutical ingredients.
Preparation Method:
- 3-(2-Naphthyl)phenylboronic acid can be synthesized by different methods. One commonly used method is to prepare by aromatic substitution reaction on the basis of phenylboronic acid.
-The specific preparation method can refer to the relevant literature of organic synthetic chemistry.
Safety Information:
-This compound is generally considered to be relatively safe under normal use conditions, but laboratory safety procedures must be followed.
-Avoid contact with skin, eyes and administration when handling this compound.
-Wear appropriate protective equipment, such as lab gloves, safety glasses and lab coats.
-It is recommended to operate in a well-ventilated area to avoid inhaling the dust or vapor of the compound.
-In case of contact with this compound, rinse immediately with plenty of water and seek medical assistance.
Last Update:2024-04-09 15:18:00